Abstract: It has been proved that running has a lot of benefits,such as enhancing cardiovascular function,physical and mental health.However,there are too much injuries associated with running.In today's bare foot running,or wearing ‘barefoot’ shoes running trends,this paper summarizes a large number of high level research papers in order to compare similarities and differences of shoes and barefoot runners by kinematic measurements,energy and biomechanics,deeply studies the running gait knowledge,and helps the patients with musculoskeletal injuries to understand the running biomechanics better,thus makes rational training plans.