Abstract: Objective: The purpose of this study was to compare the effect on oxygen uptake kinetics between high-intensity interval training and moderate-intensity continuous training. Methods:36 subjects were divided into high intensity interval training group (HIT group) , moderate-intensity continuous training (MCT group, ) and the control group (NOT) . The subjects of MCT and HIT were trained respectively for 6 weeks, the four tests were performed before the intervention in the middle of it and after it, including the ramp incremental load exhaustive test (ramp) , and oxygen uptake kinetics of moderate intensity and high intensity continuous cycling. Results: After6-week, the intervention showed higher post value than the mid and the pre of VO ₍2 max) /kg, VO₂-VAT, VO₂-VAT (P<0.05, P<0.01) , Waat-VAT in HIT and MCT;There were significant differ-ence between the above parameters between three groups (P<0.05) , but only between the HIT, MCT group with NOT group, no significant difference between HIT and MCT. There was no significant differences in A slop and AOUES between three groups (P>0.05) . Only τ ( Tau, OUE Time Constant, ) value showed significant difference between group effects (F=3.652 P=0.04<0.05) , in moderate-intensity OUK parameters, which was the two intervention groups of MCT and HIT with and control group respectively, but not in pre and med between HIT (P>0.05) ;TD and A value, in each group at different stage between groups, had no significant difference (P>0.05) . There was significant effect between groups on A₁ (A, oxygen consumption amplitude) value in high intensity exercise (F=4.439, P=0.011<0.05) , not only between MCT and HIT with NOT groups, but also between HIT and MCT (P=0.011>0.05) , A₁ of HIT group was significantly higher than the same period in MCT group (1893.9 + 132.1 vs 1632.3 + 340, P<0.05) ;and for the τ₁, after 6-week intervention, there were significant group effect (F= 9.083, P<0.01) in three groups, τ₁ value was decreased significantly in MIT and HIT group (P<0.05) ;τ₁ value of HIT group was significantly higher than that of NOT group (Mid :42.5+3.8 vs. 53.7+4.3, P<0.01) after 3 weeks, but after 6 weeks in MCT group (post :43.1+4.6 vs. 53.4+6) . A₂ value of HIT group has significantly reduced (P<0.05) after 3 weeks (mid) , and the post value was significantly lower than the MCT group and the NOT group after 6 weeks (P<0.01) , while there was no significantly difference (P>0.05) between the MCT group and the NOT group in different stage. τ₂ value was increased with no significant difference (P>0.05) . Conclusions: High-intensity interval training and moderate-intensity continuous training can improve cardiopulmonary endurance evaluation parameters of the VO ₍2 max) , VAT, but the improvement showed no significant difference between two training modes;No significant effect was found on oxygen uptake kinetics in moderate-intensity continuous cycling, but more advantages were showed in increasing response rate of oxygen consumption and reducing the slow component of oxygen uptake kinetics in high intensity interval training.