The Ganoderma Sinensis Effect in the Exhaustive Rat of Resistant Sport Fatigue and Resistant Tissue Damage

Objective:This paper mainly discusses replenishing the Ganoderma sinensis polysaccharide powder to the influence of exercise performance, energy metabolism and the tissue damage caused by the male SD rat exhaustive exercise.Method:40 male SD rats are divided into 5 groups at random and there are 8 rats in each group of which respectively are control group, exhaustive contrast group, exhaustive low dosage group, exhaustive medium dosage group and exhaustive high dosage group.Exhaustive dose group rat respectively feed in 100 mg/kg·d, 200 mg/kg·d and 500mg/kg·d dosage of Ganoderma sinensis polysaccharide powder in limosis, and feed the control group and exhaustive contrast group rat the isodose normal saline.After feeding for 30 days, kill the control group rats directly, and kill the four exhaustive groups which do the running sports until exhausted and then collect the blood, muscle and liver sample, and respectively measure the GLU (glucose) , LAC (lactic acid) in the blood plasma, and the BUN (blood urea nitrogen) concentration as well as the AST (aspartate aminotransferase) , ALT (alanine aminotransferase) , CK (creatine kinase) and LDH (lactic dehydrogenase) activity.And measure the weight, running time (exhaustive time) , hepatic glycogen and muscle glycogen content.Result:in the energy metabolism aspect, compared with group C, the group E of the muscle glycogen content and blood sugar concentration reduced conspicuously, and the BUN (blood urea nitrogen) concentration increased conspicuously (P<0.05) ;compared with group E, group EM of the blood sugar concentration and muscle glycogen content reduced conspicuously, and the group EH of the muscle glycogen reduced conspicuously (P<0.05) , there was no any conspicuous difference about the other data.In the running aspect, compared with group E, group EL and group EH lengthen conspicuously (P<0.05) , what's more, group EH conspicuously lengthen more than group EL, while group EM only appeared the trend of increasing.In the tissue damage aspect, the group E blood plasma AST, ALT, CK and LDH activity are conspicuously higher than group C (P<0.05) .Compared with group E, the AST, ALT, CK and LDH activity in the group EL, group EM and group EH did not have any conspicuous difference.Conclusion:replenish the Ganoderma sinensis polysaccharide powder can conspicuously enhance the rat exercise performance and effect of anti-mobility fatigue, which can reduce the cardiac muscle, skeletal muscle and liver damage in certain degree;to replenish high dosage (500mg/kg·d) Ganoderma sinensis polysaccharide powder in addition can take best effect on the anti-mobility fatigue, which indicates that in certain range, it exist the energy efficiency relationship.