Meta-Analysis of Different Forms of Exercise Effects on HbA1c Percentage and Part of Body Composition in Patients with Type 2 Diabetes
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Graphical Abstract
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Abstract
Objective:To evaluate the effect of different exercise on HbA1c% and BMI,body fat percentage and body fat mass index in patients with type 2diabetes.Methods:Electronic search of PubMed,EBSCO host,Elsevier,WOS and CNKI database,for a period of 1990 to 2016all literature.Collect all randomized controlled comprehensive trials of exercise intervention in patients with type 2diabetes mellitus.Cochranc bias risk assessment tools of the included literature into the methodological quality assessment;the use of software ReMan5.3.5to get data adults patients with type2 diabetes mellitus,2included articles were of ordinary quality,6articles were of high quality.Meta-analysis results:HbA1c% subgroup analysis with aerobic training group compare with resistance training group MD=-0.29(95%CI,I2= 60%,P<0.0001);comprehensive training compare with aerobic training MD=-0.19(95%CI,I2=33%,P =0.009);comprehensive training compare with resistance training MD=-0.49(95% CI,I2=72%,P< 0.00001).BMI subgroup analysis of resistance training of type 2diabetic patients with BMI improvement MD=-0.05(95% CI,I2=59%,P=0.40);comprehensive training compare with aerobic training MD=-0.06(95% CI,I2=37%,0.52).Body fat mass subgroup analysis with aerobic training group compare with resistance training group MD=-0.35(95%CI,I2=6%,P= 0.29);comprehensive training compare with aerobic training is MD=-0.46(95%CI,I2=0%,P=0.16),comprehensive training group compare with resistance training group MD=-0.80(95%CI,I2=0%,P=0.01).Body fat percentage subgroup analysis of aerobic training on type 2diabetes patients with body fat per-centage change compare with control group MD=-0.47(95%CI,I2=87%,P=0.25);comprehensive training compare with resistance training is MD=-0.55(95% CI,I2=86%,P=0.07).Conclusion:comprehensive training is the best way to control blood glucose in type2 diabetic patients.Resistance aerobic training had no significant effect on type 2diabetes' body fat percentage;comprehensive training had no significant advantage on BMI,body fat weight and body fat percentage in patients with type 2diabetes.
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