Effect of Astaxanthin and Exercise on Antioxidant Capacity of Human Body,Blood Lactic Acid and Blood Uric Acid Metabolism

Objective:Make a research of the effect of intake of astaxanthin as well as acute and high-intensity exercise on antioxidant capacity of human body, blood lactic acid and blood uric acid metabolism.Methods:select 16 male students from physic culture institute and classify them into Experimental Group A and Control Group B at random (8person per each group) .The students from Group A take astaxanthin with mild moderate dose (12mg/d) for 28 days, while those from Group B take placebo for 28 days.Four weeks later, all subjects will do acute high-intensity exercise, that is, riding cycle ergometer with all strength 30seconds×3/at three minutes interval, loading a weight of 0.075kg/kg.Blood sample of all subjects are collected before taking medicine, after taking medicine (before exercise) , immediately after the exercise, one hour after the exercise respectively to test the antioxidant capacity, blood lactic acid and blood uric acid.Results:1) Intake of astaxanthin with mild moderate dose for 4weeks can obviously enhance the body antioxidant capacity of subjects (P<0.01) , lower blood lactic acid level (P<0.05) and blood uric acid level (P<0.05) .2) Instantly after acute high-intensity exercise, the antioxidant capacity of the two groups decline without exception (P<0.05) , the blood lactic acid of two groups evidently rise (P<0.01) , however, the antioxidant capacity of Experimental Group is obviously higher than that of Control Group (P<0.05) , the blood lactic acid level of Experimental Group is lower than that of Control Group (P<0.05) ;In spite of decline of blood uric acid of the two groups instantly after exercise, however there is no statistics difference, the value of the Experimental Group is still slightly lower than Control Group (P<0.05) .3) One hour after exercise, the antioxidant capacity of the two groups obviously go up without exception (P<0.05) and the value of Experimental Group is obviously higher than that of Control Group (P<0.01) .The blood lactic acid of two groups dramatically decline (P<0.01) and the value of Experimental Group is obviously lower than that of Control Group (P<0.05) .The blood uric acid of two groups dramatically rise (P<0.01) and the value of Experimental Group is obviously lower than that of Control Group (P<0.05) .Conclusion:1) Continuous intake of astaxanthin with mild moderate dose for 4 weeks can obviously enhance antioxidant capacity of human body at a resting state, reduce the content of blood lactic acid and blood uric acid.2) Improve the reduction and restoration of antioxidant capacity of human body after a acute and high-intensity exercise, the generation and elimination speed of blood lactic acid and blood uric acid.